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21/09/2015

12.00 pm, Seminar Room on the 1st Floor

To Be Announced

Dr. Igal Szleifer (Northwestern University, USA)

24/09/2015

12.00 pm, Seminar Room on the 1st Floor

Atomic force microscopy: What we can learn from prodding biomolecules

Dr. Bart Hoogenboom (University College London, UK)

Life depends on intricate machinery that operates at the molecular level. I will show several examples on how we use atomic force microscopy (AFM) to prod and visualise this machinery at ~1 nm spatial resolution. This includes resolving variations of the Watson-Crick double helix structure in single DNA molecules; real-time imaging of membrane attack by bacterial toxins; and measuring and understanding the nanomechanics of polymers that determine transport into and out of the cell nucleus.